Replaceable You

Adventures in Human Anatomy

By: Mary Roach

TRANSPLANT SURGERY BIOMEDICAL ENGINEERING PLASTIC & RECONSTRUCTIVE SURGERY

Description

The body is the most complex machine in the world, and the only one for which you cannot get a replacement part from the manufacturer. For centuries, medicine has reached for what's available--sculpting noses from brass, borrowing skin from frogs and hearts from pigs, crafting eye parts from jet canopies and breasts from petroleum by-products. Today we're attempting to grow body parts from scratch using stem cells and 3D printers. How are we doing? Are we there yet?

In Replaceable You, Mary Roach explores the remarkable advances and difficult questions prompted by the human body's failings. When and how does a person decide they'd be better off with a prosthetic than their existing limb? Can a donated heart be made to beat forever? Can an intestine provide a workable substitute for a vagina?

Roach dives in with her characteristic verve and infectious wit. Her travels take her to the OR at a legendary burn unit in Boston, a "superclean" xeno-pigsty in China, and a stem cell "hair nursery" in the San Diego tech hub. She talks with researchers and surgeons, amputees and ostomates, printers of kidneys and designers of wearable organs. She spends time in a working iron lung from the 1950s, stays up all night with recovery techs as they disassemble and reassemble a tissue donor, and travels across Mongolia with the cataract surgeons of Orbis International.

Irrepressible and accessible, Replaceable You immerses readers in the wondrous, improbable, and surreal quest to build a new you.

The body is the most complex machine in the world, and the only one for which you cannot get a replacement part from the manufacturer. For centuries, medicine has reached for what's available--sculpting noses from brass, borrowing skin from frogs and hearts from pigs, crafting eye parts from jet canopies and breasts from petroleum by-products. Today we're attempting to grow body parts from scratch using stem cells and 3D printers. How are we doing? Are we there yet?

In Replaceable You, Mary Roach explores the remarkable advances and difficult questions prompted by the human body's failings. When and how does a person decide they'd be better off with a prosthetic than their existing limb? Can a donated heart be made to beat forever? Can an intestine provide a workable substitute for a vagina?

Roach dives in with her characteristic verve and infectious wit. Her travels take her to the OR at a legendary burn unit in Boston, a "superclean" xeno-pigsty in China, and a stem cell "hair nursery" in the San Diego tech hub. She talks with researchers and surgeons, amputees and ostomates, printers of kidneys and designers of wearable organs. She spends time in a working iron lung from the 1950s, stays up all night with recovery techs as they disassemble and reassemble a tissue donor, and travels across Mongolia with the cataract surgeons of Orbis International.

Irrepressible and accessible, Replaceable You immerses readers in the wondrous, improbable, and surreal quest to build a new you.

This Edition

Format
Paperback
Pages
288
Published
September 1, 2026
ISBN-13
9781324134268
Language
English
Publisher
W. W. Norton & Company, Incorporated

Trade Reviews

"Replaceable You by turns surprises and delights, revealing information that even I didn’t know…These curious facts, with attendant and laugh-inducing footnotes, keep us turning the pages."

"Since she burst onto the scene with 2003’s Stiff: The Curious Lives of Human Cadavers, the science writer Mary Roach has been grossing readers out with curiosity, humanity—and alarming gusto. And we can’t look away."

"Readers will feel awed at all the body can do and how it is made, as well as admiration for humanity’s per­sistence in exploring its limits—whether when confronted with a malfunctioning organ or the desire for a more plump derriere. Replaceable You will delight Roach’s fans and surely garner some more."

"Mary Roach offers a fascinating tour of the wonderful world of regenerative medicine."

"The humanity that [Roach] brings is such a wonderful base for how our bodies fail us sometimes and what we are trying to do to bring them back."

Additional Editions

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